Verdict

For a NAS or any RAID array, the ST4000VN006 is the clear pick - it's a CMR drive, while the ST4000DM004 uses SMR recording, which is not recommended for RAID. Only consider the ST4000DM004 for single-drive or archival use.

ST4000DM004 ST4000VN006
Capacity 4 TB 4 TB
Recording tech SMR CMR
RAID / NAS safe No Yes
Class Desktop NAS
Spindle speed 5400 RPM 5400 RPM
Cache 256 MB 256 MB
Noise (idle) 22 dB -
Fill Air Air
Interface SATA SATA
Failure rate (AFR) - -
Price / TB $50.18 $52.45

Highlighted cells mark the stronger spec for a NAS build. Failure rates from Backblaze Drive Stats where available; $/TB shows once live prices are wired.